US 12,104,162 B2 · Insect inhibitory proteins

Abstract

Pesticidal protein exhibiting toxic activity against Lepidopteran and Hemipteran pest species are disclosed, and include, but are not limited to, TIC2199. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding the disclosed pesticidal protein. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran and Hemipteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the protein of the present invention in a biological sample, and methods of controlling Lepidopteran and Hemipteran species pests using TIC2199 pesticidal protein are also provided.

Claims28

Dependent claims

A recombinant nucleic acid molecule comprising a heterologous promoter operably linked to a polynucleotide segment encoding a pesticidal protein or pesticidal fragment thereof, wherein:

a. said pesticidal protein comprises the amino acid sequence of SEQ ID NOs:2, 4, 7, 10, 13, 15, or 17;
or
b. said pesticidal protein comprises an amino acid sequence having at least 99% amino acid sequence identity to SEQ ID NOs:2, 4, 7, 10, 13, 15, or 17;
wherein said pesticidal protein exhibits activity against a Lepidopteran or a Hemipteran insect.

1 more element

Dependencies are inferred from the claim text.

Facts

Application

17/854,198Filed 30 Jun 2022 · us provisional application

Priority

8 Jul 2021

Published

US 2023/0013686 A119 Jan 2023

Granted

1 Oct 2024

Term ends

Not estimatedThe source records don’t support an estimate.

Classification21 codes

C12N 15/8286
For biotic stress resistance, pathogen resistance, disease resistance: for insect resistance
A01N 37/46
Containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton…
A01N 57/16
Having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds: containing heterocyclic radicals
A01N 63/22
Bacteria; Substances produced thereby or obtained therefrom: bacillus

Insect inhibitory proteins

Life of this patent

Insect inhibitory proteins

Life of this patent

Abstract

Claims28