Method and apparatus for direct in-vivo, electrical and chemical monitoring and stimulation of the endometrial cavity

A system for in-vivo intrauterine electromyography of tissue of at least one of an endometrial cavity, an endometrial junctional zone, and an endometrium comprising:

• a flexible structure sized for insertion into said endometrial cavity, sufficiently flexible to conform to said endometrial cavity so as not to cause muscle stimulation, and having a width of less than 5 mm, including a set of insulated conductive filaments and comprising:
• a first end portion of the flexible set of insulated conductive filaments including a connector comprising a plurality of connections,
• a second end portion of the flexible set of insulated conductive filaments including an array of electrodes configured for acquiring intrauterine electromyography measurements and disposed along a length of said second end portion, wherein said electrodes are spaced apart from each other to provide a plurality passive electrical measurements, each electrode of said array providing a measurement of a different region of said tissue of said at least one of said endometrial cavity, an endometrial junctional zone, and an endometrium, which electrical measurements including measurement of electrical activity associated with uterine contractility;
• and
• data acquisition and signal processing hardware configured to:
• receive said plurality of electrical measurements;
• and
• identify and characterize non-pregnant uterine contractility using said plurality of electrical measurements.