Combination of plasma immunoglobulin and antigen-specific immunoglobulin for the modification of the immune system and the treatment or prevention of allergic diseases
AssigneeNetwork Immunology Inc.
InventorsGeoffrey William Hoffmann, Reginald M. Gorczynski
Life of this patent
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Abstract
A method of use of plasma immunoglobulin, such as intramuscular immunoglobulin, in combination with polyclonal antigen-specific immunoglobulin in the treatment or prevention of allergic disease is provided. Also provided is a pharmaceutical composition including plasma immunoglobulin in combination with polyclonal antigen-specific immunoglobulin.
Claims18
A pharmaceutical composition for the treatment or prevention of allergic disease in a mammalian subject, said pharmaceutical composition comprising a combination of:
- (a) pooled plasma immunoglobulin;
- and
- (b) additional antigen specific immunoglobulin, wherein said antigen-specific immunoglobulin is selected from the group consisting of polyclonal anti-tetanus toxoid immunoglobulin, polyclonal anti-hepatitis B immunoglobulin, polyclonal anti-rabies immunoglobulin, and polyclonal anti-varicella immunoglobulin.
A method of treating or preventing an allergic disease, comprising administering to a mammalian subject in need thereof a combination of
- (a) pooled plasma immunoglobulin;
- and
- (b) additional antigen-specific immunoglobulin.
A method of treating or preventing an ovalbumin allergy or peanut allergy, comprising administering to a mammalian subject in need thereof a pharmaceutical composition comprising a combination of pooled plasma immunoglobulin and antigen-specific immunoglobulin.
Dependencies are inferred from the claim text.