US 12,084,481 B2 · HV1 modulators and uses

Abstract

The present invention provides novel agents for modulation of Hv1 channels. The present invention provides agents for activating and/or inhibiting Hv1 channel function and/or activity, and reagents and methods relating thereto.

Claims11

Dependent claims

A voltage-gated proton channel (Hv1) inhibitor comprising at least two polypeptide components, wherein each component has an amino acid sequence comprising SEQ ID NO:

129.

Dependencies are inferred from the claim text.

Facts

Application

17/684,346Filed 1 Mar 2022 · continuation

Priority

30 Dec 2016

Published

US 2022/0289800 A115 Sep 2022

Granted

10 Sep 2024

Term ends

Not estimatedThe source records don’t support an estimate.

Classification10 codes

C07K 7/06
Linear peptides containing only normal peptide links: having 5 to 11 amino acids
C07K 14/43518
From arachnidae: from spiders
C07K 7/08
Linear peptides containing only normal peptide links: having 12 to 20 amino acids
C07K 14/43522
From arachnidae: from scorpions

Family

Application62/441,097Us provisional application · filed 30 Dec 2016

Application62/447,433Us provisional application · filed 17 Jan 2017

PCT/US2017/068896Parent of this continuation · filed 29 Dec 2017

US 2022/0289800 A1Pre-grant publication · published 15 Sep 2022

Application16/474,906Parent of this continuation

US 11,274,130 B2Parent of this continuation

US 2019/0330285 A1Published application

US 12,084,481 B2This patent

From the US filing history. Foreign family members aren’t listed.

Abstract

Facts

Application

17/684,346Filed 1 Mar 2022 · continuation

Priority

30 Dec 2016

Published

US 2022/0289800 A115 Sep 2022

Granted

10 Sep 2024

Term ends

Not estimatedThe source records don’t support an estimate.

Classification10 codes

C07K 7/06
Linear peptides containing only normal peptide links: having 5 to 11 amino acids
C07K 14/43518
From arachnidae: from spiders
C07K 7/08
Linear peptides containing only normal peptide links: having 12 to 20 amino acids
C07K 14/43522
From arachnidae: from scorpions

Family

Application62/441,097Us provisional application · filed 30 Dec 2016

Application62/447,433Us provisional application · filed 17 Jan 2017

PCT/US2017/068896Parent of this continuation · filed 29 Dec 2017

US 2022/0289800 A1Pre-grant publication · published 15 Sep 2022

Application16/474,906Parent of this continuation

US 11,274,130 B2Parent of this continuation

US 2019/0330285 A1Published application

US 12,084,481 B2This patent

From the US filing history. Foreign family members aren’t listed.

HV1 modulators and uses

Life of this patent

Abstract

Claims11

HV1 modulators and uses

Life of this patent

Abstract

Claims11