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US 12,084,411 B2Granted
Hinokitiol analogues, methods of preparing and pharmaceutical compositions thereof
AssigneeThe Board of Trustees of the University of Illinois
InventorsMartin D. Burke, Anthony S. Grillo, Alexander G. Cioffi, Anna SantaMaria, Daniel Blair, Andrew Blake
Life of this patent
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Abstract
Disclosed are analogues of hinokitiol, methods for preparing them, and pharmaceutical compositions thereof. Also disclosed are methods for their use in treating iron-related diseases.
Claims25
A compound having a structure according to Formula (I):
- or a salt thereof;
- wherein
- Ra is selected from the group consisting of
- Rb is hydrogen or methyl;
- provided that if Ra is
- then Rb is methyl.
3 more elements
A compound selected from:
- or a salt thereof.
A compound selected from the group consisting of:
- and salts thereof;
- and salts thereof;
- and
- and salts thereof.
1 more element
Dependencies are inferred from the claim text.