Model based PBS optimization for flash therapy treatment planning and oncology information system

An electronic system comprising:

• a memory;
• and
• a processor in communication with the memory, wherein the processor is operable to execute instructions for performing a method comprising:
• receiving an input parameter for each voxel of a plurality of voxels of a treatment map, wherein the input parameter is included in a radiotherapy treatment plan;
• generating a biological outcome map that assigns a respective value to said each voxel of the treatment map, wherein the respective value for said each voxel is based on a model that relates a value of the input parameter for said each voxel to a biological outcome for said each voxel;
• and
• modifying the radiotherapy treatment plan based on the respective value for said each voxel comprised in the biological outcome map, wherein said modifying comprises adjusting the value of the input parameter to modify the respective value for said each voxel;
• wherein said modifying further comprises implementing quantitative time-dependent model-based charged particle pencil beam scanning optimization for FLASH therapy.

A non-transitory computer-readable storage medium embodying instructions that are executed by a processor to cause the processor to perform a method comprising:

• receiving an input parameter for each voxel of a plurality of voxels of a treatment map, wherein the input parameter is included in a radiotherapy treatment plan;
• generating a biological outcome map that assigns a respective value to said each voxel of the treatment map, wherein the respective value for said each voxel is based on a model that relates a value of the input parameter for said each voxel to a biological outcome for said each voxel;
• and
• modifying the radiotherapy treatment plan based on the based on the respective value for said each voxel comprised in the biological outcome map, wherein said modifying comprises adjusting the value of the input parameter to modify the respective value for said each voxel;
• wherein said modifying further comprises implementing quantitative time-dependent model-based charged particle pencil beam scanning optimization for FLASH therapy.