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US 12,083,147 B2Granted
Compositions and methods for the treatment of contact lens discomfort
AssigneeAzura Ophthalmics Ltd.
InventorsCharles Bosworth, Yair Alster, Hila Epstein-Barash, Omer Rafaeli, Marc Gleeson
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Abstract
Described herein are compositions and methods for the treatment of contact lens discomfort (CLD) and/or lid wiper epitheliopathy (LWE). Such compositions comprise keratolytic agents, such as salicylic acid, selenium disulfide, or the like. Topical administration of such compositions to the inner surface of the eyelid provides therapeutic benefit to patients suffering from contact lens discomfort (CLD) and/or lid wiper epitheliopathy (LWE).
Claims20
A method for improving vision in an individual wearing a contact lens, the method comprising:
- (i) topically administering to an eye or an eyelid associated with the eye of the individual a pharmaceutically acceptable composition, the composition comprising a therapeutically-effective amount of at least one keratolytic agent and an ophthalmically-acceptable carrier;
- and
- (ii) wearing a contact lens in the eye, wherein vision of the individual is improved relative to vision of the individual in the absence of the topical administration of the composition, and wherein the individual has not been diagnosed with meibomian gland dysfunction (MGD).
Dependencies are inferred from the claim text.