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US 12,077,610 B2Granted
Peptides and other agents for treating pain and increasing pain sensitivity
AssigneeThe Research Foundation for The State University of New York
InventorsArindam Bhattacharjee, Kerri Pryce
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Abstract
Described herein are peptides that can be used to treat pain or increase pain sensitivity in subject in need of treatment. Additionally, peptides of the present disclosure can be administered with an analgesic agent and/or anesthetic agent. Peptides of the present disclosure are suitable for use when a subject in need of treatment has an injury, a chronic disease, a chronic inflammation, Morton's neuroma, operative/post-operative pain, or a combination thereof.
Claims10
A method for treating pain comprising:
- a) a subject in need of treatment for pain;
- b) administering to said subject a therapeutically effective amount of a composition selected from the group consisting of a fifteen amino acid peptide having the sequence of X1X2X3X4X5PPSYX8X9VX10X11X12 (SEQ ID NO:114) and a MAGI-1 antisense ribonucleic acid;
- and
- c) reducing said pain of said subject.
1 more element
Dependencies are inferred from the claim text.