Demineralized bone matrix fibers, methods of making and using them
AssigneeWarsaw Orthopedic, Inc.
InventorsGregory Scott McGraw, David R. Kaes
Life of this patent
Estimating the term…
Abstract
A device for mixing a bone material with a liquid is provided. The device comprises a chamber having a proximal end and a distal end, and the bone material disposed within the chamber, the bone material comprising a DBM pellet of milled and lyophilized demineralized bone fibers; and a plunger having at least a portion slidably disposed within the proximal end of the chamber and configured to dispense the bone material mixed with liquid from the distal end of the chamber, when the plunger is in an extended position.
Claims13
A method of preparing a demineralized bone matrix pellet, the method comprising providing a plurality of first bone fibers having a diameter from about 0.6 mm to about 8.0 mm;
- mixing the plurality of first bone fibers with a plurality of second bone fibers having a diameter from about 0.5 mm to about 0.05 mm to form a mixture of first bone fibers and second bone fibers;
- demineralizing the mixture of first bone fibers and second bone fibers to form a demineralized bone matrix slurry;
- adding the demineralized bone matrix slurry to a mold;
- and drying the demineralized bone matrix slurry to form a demineralized bone matrix pellet in the mold, wherein the first bone fibers have their diameter larger relative to the diameter of the second bone fibers, wherein the ratio of first bone fibers to second bone fibers is about 80:20 respectively or about 90:10 respectively in the mixture.
Dependencies are inferred from the claim text.