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AssigneeAltria Client Services LLC
InventorsSreepriya Pramod, Marcos Fernando de Godoy Lusso, Jesse Frederick, Andrew Carl Adams, Dongmei Xu
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The present disclosure provides tobacco Nic1b locus and associated genes. Also provided are tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants. Further provided are compositions and methods for producing tobacco plants having novel mutations or alleles to reduce nicotine levels. Further provided are sequence polymorphisms and molecular markers for breeding tobacco with reduced nicotine or alkaloids while maintaining tobacco leaf grade and tobacco product quality.
A tobacco plant, or part thereof, comprising a non-natural mutation that introduces a stop codon into SEQ ID NO:
A tobacco plant, or part thereof, comprising a non-transgenic and non-natural mutation that introduces a stop codon into SEQ ID NO:3, wherein said non-transgenic and non-natural mutation reduces the nicotine level of said tobacco plant to below 60% of the nicotine level of a control tobacco plant when grown in similar growth conditions, wherein said tobacco plant produces a leaf, when cured, having a USDA grade index value comparable to the USDA grade index value of said control plant, wherein said control plant does not comprise said non-transgenic and non-natural mutation, and wherein said tobacco plant and said control tobacco plant are Nicotiana tabacum plants.
Dependencies are inferred from the claim text.