Chromatography medium
AssigneePuridify Ltd.
InventorsOliver Hardick, Daniel Gilbert Bracewell, Stewart Dods
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Abstract
The present invention provides a process for preparing a functionalised polymeric chromatography medium, which process comprises (I) providing two or more non-woven sheets stacked one on top of the other, each said sheet comprising one or more polymer nanofibres, (II) simultaneously heating and pressing the stack of sheets to fuse points of contact between the nanofibres of adjacent sheets, and (III) contacting the pressed and heated product with a reagent which functionalises the product of step (II) as a chromatography medium.
Claims12
A chromatography medium suitable for isolating biological molecules from mobile phases, wherein the chromatography medium comprises a stack of multiple non-woven sheets, wherein each non-woven sheet comprises polymer nanofibres and has a density of at least 200 kg/m3, wherein the stack of multiple non-woven sheets comprises fused points of contact between each adjacent sheet, and wherein said polymer nanofibres have mean diameters from 10 nm to 1000 nm.
Dependencies are inferred from the claim text.