Conjugate vaccine targeting a disease-causing biological protein
AssigneesOsaka University, Funpep Co., Ltd.
InventorsHironori Nakagami, Ryuichi Morishita, Akiko Tenma
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Abstract
The present invention provides a vaccine containing a complex of a peptide consisting of the amino acid sequence of SEQ ID NO: 1 and an epitope of a disease-causing biological protein such as DPP4, IL-17A, IgE, S100A9 or PCSK9, which vaccine uses a less antigenic carrier protein and is capable of inducing antibody production to serve as an effective vaccine.
Claims9
A vaccine comprising a complex of a peptide consisting of the amino acid sequence of SEQ ID NO:
- 1 and an epitope of a disease-causing A biological protein, wherein the biological protein is immunoglobulin E (IgE).
An immunogenic composition comprising a complex of a peptide consisting of the amino acid sequence of SEQ ID NO:
- 1 and an epitope of a disease-causing biological protein, and an epitope of a disease-causing biological protein, wherein the biological protein is immunoglobulin E (IgE).
A method for induction of producing antibody by a biological protein, the method comprising administering, to an animal, an effective amount of a complex of a peptide consisting of the amino acid sequence of SEQ ID NO:
- 1 and an epitope of the biological protein, wherein the biological protein is immunoglobulin E (IgE).
A complex for use in induction of producing antibody by a biological protein, the complex of a peptide consisting of the amino acid sequence of SEQ ID NO:
- 1 and an epitope of the biological protein, wherein the biological protein is immunoglobulin E (IgE).
A complex of a peptide consisting of the amino acid sequence of SEQ ID NO:
- 1 and an epitope of the biological protein, wherein the biological protein is immunoglobulin E (IgE).
Dependencies are inferred from the claim text.