Methods and systems to control particles and implantable devices

A platform comprising the following modules:

• one or more particles, each of said particles having a size between about 100 nm and about 1000 μm and comprising embedded logic and microelectromechanical (MEM) components, each of said particles further comprising a remote power-harvesting component configured to harvest power from ultrasonic signals of a predetermined frequency to power said MEM components thereof;
• a delivery and retraction module configured to deliver and retract said particles;
• an external signal generator;
• an imaging module configured to monitor said particles;
• and
• an integration module configured to receive inputs from and to provide output control commands to said particles, said delivery and retraction module, said external signal generator and said imaging module;
• wherein:
• said particles, said delivery and retraction module, said external signal generator, said imaging module, and said integration module are configured to interact/communicate with each other;
• and are controlled internally and/or externally, thereby providing pre-determined, fully controlled, precise delivery of said particles in vitro, in vivo, and/or in a patient;
• and
• the power-harvesting component comprises a flexible element having a resonance frequency which is equal to said predetermined frequency and a piezoelectric element connected to said flexible element.