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US 12,066,449 B2Granted
High throughput system for performing assays using electrochemiluminescence including a consumable shaking apparatus
AssigneeMeso Scale Technologies, LLC.
InventorCarl Theodore Edens
Life of this patent
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Abstract
The present invention relates to a system for performing assays on a solid phase to measure the level of analyte in a sample. Such a system may perform immunoassays using electrochemiluminescence (ECL) including a counterbalanced orbital shaking apparatus for assay consumables. The counterbalanced orbital shaking apparatus also incubates the assay consumables, and has a cooling system to maintain a preset temperature within the shaking apparatus.
Claims17
An electrochemiluminescence (ECL) immunoassay system comprising:
- a housing that encloses a pipette dispenser, a plurality of multi-well plates adapted to hold ECL complexes attached to electrodes contained in the plurality of multi-well plates, the housing further including a blower, an ECL reader, a hood, a chimney connected to the hood, and at least one cooler;
- wherein the plurality of multi-well plates are sized and dimensioned to be stored in an incubator,
- wherein the at least one cooler is located proximate to a back surface of the housing and further includes an inlet, and
- wherein the blower is configured to pull air from the housing through at least one airflow channel disposed within the incubator, and said air pulled from the housing by the blower is ducted through the hood and the chimney to the inlet of the at least one cooler to cool said air, and cooled air is returned to the housing.
1 more element
An assay consumable storage assembly, comprising:
- a housing further including:
- a pipette dispenser;
- a plurality of multi-well plates configured to hold electrochemiluminescence (ECL) complexes attached to electrodes contained in the plurality of multi-well plates;
- a blower configured to pull air from the housing through at least one airflow channel of an incubator configured for storing the plurality of multi-well plates;
- at least one cooler located proximate to a back surface of the housing, the at least one cooler further including an inlet;
- a hood connected to a chimney and configured for ducting the air pulled from the housing by the blower through the chimney to the inlet of the at least one cooler;
- a plenum configured for returning the air cooled by the at least one cooler into the housing;
- and
- an ECL reader.
6 more elements
Dependencies are inferred from the claim text.