Methods and compositions for protein sequencing
AssigneeQuantum-Si Incorporated
InventorsBrian Reed, Manjula Pandey
Life of this patent
Estimating the term…
Abstract
Aspects of the application provide methods of identifying and sequencing proteins, polypeptides, and amino acids, and compositions useful for the same. In some aspects, the application provides amino acid recognition molecules, such as amino acid binding proteins and fusion polypeptides thereof. In some aspects, the application provides amino acid recognition molecules comprising a shielding element that enhances photostability in polypeptide sequencing reactions.
Claims17
An amino acid recognition molecule comprising a polypeptide having at least a first amino acid binding protein and a second amino acid binding protein joined end-to-end, wherein the first and second amino acid binding proteins are separated by a linker comprising at least two amino acids, and wherein the polypeptide has an amino acid sequence that is at least 90% identical to an amino acid sequence selected from any one of SEQ ID NOs:
- 249-271.
Dependencies are inferred from the claim text.