Enterovirus multi-antigen epitope fusion protein, gene, vaccine, and preparation method thereof

Abstract

An enterovirus multi-antigen epitope fusion protein, a gene, a vaccine and a preparation method thereof are provided, relating to the field of vaccine preparation technologies. The amino acid sequence of the enterovirus multi-antigen epitope fusion protein is shown in SEQ ID NO: 4. The vaccine is prepared by adopting the preparation method of a genetically engineered protein vaccine, and the prepared vaccine has stronger specificity. After protein purification, there are fewer impure proteins and more specific antigen proteins, thus improving the effectiveness and safety of the combined vaccine.

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