Co-crystals or salts of psilocybin and methods of treatment therewith
AssigneeReset Pharmaceuticals, Inc.
InventorsJohn Knight, Talbir Austin
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Abstract
The invention relates to a co-crystal or salt comprising psilocybin and a co-former. The co-crystal or salt is useful in methods of treating or preventing a disease or condition selected from depression, anxiety, death anxiety, demoralization, adjustment disorders, hopelessness, suicidal ideation, desire for hastened death, cocaine-related disorders, opioid-related disorders and stimulant-related disorders in a patient. A kit comprising the co-crystal or salt is also described.
Claims13
A co-crystal or salt comprising psilocybin and a co-former, wherein the co-former is piperazine, and wherein the co-crystal or salt is in the form of crystalline piperazine Pattern 1 having an x-ray powder diffraction pattern comprising peaks at 13.1°, 15.4° and 24.4°±0.2° 2θ.
A co-crystal or salt comprising psilocybin and a co-former, wherein the co-former is piperazine, and wherein the co-crystal or salt is in the form of crystalline piperazine Pattern 2 having an x-ray powder diffraction pattern comprising peaks at 13.1°, 17.3° and 24.6°±0.2° 2θ.
Dependencies are inferred from the claim text.