Compositions and methods of using itaconic acid derivatives

A compound of Formula (12):

• wherein:
• R21 and R26 are hydrogen
• R16, R17, R19, R20, R22, and R25 are hydrogen,
• R18 is selected from the group consisting of hydrogen, deuterium, C1-C6 alkyl, halo, CN, CF3, —COOH, —OH, C1-C6 alkoxy, —NH2, —(C1-C6 alkyl)NH2, —(C1-C6 alkyl)NH(C1-C6 alkyl), —(C1-C6 alkyl)N(C1-C6 alkyl)2, —NH(C1-C6 alkyl), —N(C1-C6 alkyl)2, —CONH2, —NH(CO)(C1-C6 alkyl), —N(C1-C6 alkyl)CO(C1-C6 alkyl), —SO2—(C1-C6 alkyl), —(SO)NH2, (SO)NH(C1-C6 alkyl), and (SO)N(C1-C6 alkyl)2, and
• R23 and R24 are hydrogen or —CH3.