Back to results
US 12,059,444 B2Granted
Altered virus
AssigneeReplimune Limited
InventorRobert Stuart Coffin
Life of this patent
Estimating the term…
Abstract
The present invention relates to an oncolytic virus encoding a CTLA-4 inhibitor, such as an anti-CTLA-4 antibody, or an antigen binding fragment thereof.
Claims37
An oncolytic herpes simplex virus 1 (HSV1) which is strain RH018A having the accession number ECACC 16121904 modified to encode a CTLA-4 inhibitor.
Dependencies are inferred from the claim text.