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US 12,054,752 B2Granted
HLA-A2 subtype-specific PLK1-derived epitope inducing antigen-specific t cell immune response to PLK1 protein
AssigneeThe Catholic University of Korea Industry-Academic Cooperation Foundation
InventorsTai Gyu Kim, Hyun Il Cho, Un Hee Kim
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Abstract
The present invention relates to a HLA-A2 subtype-specific PLK1-derived epitope inducing an antigen-specific T cell immune response to a PLK1 protein. More specifically, a HLA-A2 subtype-specific PLK-1-derived epitope inducing an antigen-specific T cell immune response to a PLK1 protein according to the present invention can provide a CD8+ T cell immune response specific for tumor cells.
Claims7
A peptide consisting of SEQ ID NO:
- 1, wherein the peptide is specific for Human Leukocyte Antigen A*02:01 (HLA-A*02:01).
Dependencies are inferred from the claim text.