Opioid overdose rescue device

An opioid overdose rescue device to mitigate the effects of an opioid overdose in a patient who has taken an opioid comprising:

• an ingestible capsule;
• a non-refillable drug dispenser contained within the capsule and comprising an opioid antidote;
• an accelerometer contained within the capsule configured to sense movement signals within the patient's gastrointestinal tract caused by peristalsis and respiration and generate accelerometer signals;
• and
• a controller operatively coupled to the drug dispenser and the accelerometer, the controller configured to receive the accelerometer signals and produce processed accelerometer signals from the gastrointestinal tract that isolate movement signals caused by respiration to estimate a respiratory rate of the patient and to actuate drug release of the opioid antidote from the drug dispenser into the patient upon a determination that the respiratory rate falls outside a threshold value or range indicating that an opioid overdose has been detected.