System and methods for percutaneous mechanical and/or neural interface

A system suitable for use as a semi-permanent percutaneous interface configurable as a catheter comprising:

• a distal, partially external port head configured for external access to the catheter;
• a distal, top end of the catheter connected to the port head;
• wherein the port head is semi-permanently attached to adjacent tissue layers;
• a proximal, internal, bottom of the catheter extending to an internal location internal to a body;
• internal ports positionable along a length of the catheter configured for passage of fluid through the catheter;
• flow valves arranged within the port head designed to regulate fluid flow through the catheter;
• and
• bio-compatible and bio-occlusive artificial membranes (BIOCAMS) lamina providing attachment of a port head lamina and/or other concomitant BIOCAM lamina to adjacent tissue layers, including any epithelial, mesothelial or endothelial derived tissue layer such as epidermal, dermal, fascial, endothelial, endovascular, mucosal, bone, pleural, peritoneal, muscular, organ, organ region, organ layer, organ component or organ compartment or any other bodily tissue and/or any combination of these tissues and layers, wherein the lamina is configured to provide isolation of the exterior environment or any adjacent tissue, layer, component, compartment, region, or environment, and to minimize leakage from a specific internal bodily or organ environment into adjacent soft tissue or bone.