Anti-NME antibody and method of treating cancer or cancer metastasis

A monoclonal antibody comprising:

• an amino acid sequence in the heavy chain variable region comprising the following:
• in the CDR1 region NTFTEYTMH (SEQ ID NO:
• 388);
• in the CDR2 region GFNPNNGVTNYNQKFKG (SEQ ID NO:
• 389);
• and
• in the CDR3 region RYYHSLYVFYFDY (SEQ ID NO:
• 390);
• and
• an amino acid sequence in the light chain variable region comprising the following:
• in the CDR1 region SASQGISNYLN (SEQ ID NO:393);
• in the CDR2 region YTSSLHS (SEQ ID NO:
• 394);
• and
• in the CDR3 region QQYSKLPYT (SEQ ID NO:
• 395).