Back to results
US 12,044,681 B2Granted
Protein signatures for distinguishing between bacterial and viral infections
AssigneeMeMed Diagnostics Ltd.
InventorsEran Eden, Kfir Oved, Assaf Cohen-Dotan, Roy Navon, Olga Boico, Gali Kronenfeld, Meital Paz, Ellen Bamberger
Life of this patent
Estimating the term…
Abstract
Methods of diagnosing infections are disclosed. In one embodiment, the method comprises measuring the amount of each of the polypeptides TRAIL, CRP, IP10 and at least one additional polypeptide selected from the group consisting of IL-6 and PCT.
Claims9
A kit for distinguishing between a viral and a bacterial infection using a blood sample of a subject comprising:
- (i) an antibody which specifically detects TNF-related apoptosis-inducing ligand (TRAIL);
- (ii) an antibody which specifically detects Interleukin-6 (IL-6):
- (iii) an antibody which specifically detects C-reactive protein (CRP);
- and
- (iv) an antibody which specifically detects Interferon gamma-induced protein 10 (IP10), wherein the kit comprises antibodies that specifically detect no more than 5 proteins, wherein at least one of said antibodies is attached to a detectable label or a solid support.
2 more elements
Dependencies are inferred from the claim text.