Strongly Lewis acidic metal-organic frameworks for continuous flow catalysis
AssigneeThe University of Chicago
InventorsWenbin Lin, Xuanyu Feng, Pengfei Ji
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Abstract
Lewis acidic metal-organic framework (MOF) materials comprising triflate-coordinated metal nodes are described. The materials can be used as heterogenous catalysts in a wide range of organic group transformations, including Diels-Alder reactions, epoxide-ring opening reactions, Friedel-Crafts acylation reactions and alkene hydroalkoxylation reactions. The MOFs can also be prepared with metallated organic bridging ligands to provide heterogenous catalysts for tandem reactions and/or prepared as composites with support particles for use in columns of continuous flow reactor systems. Methods of preparing and using the MOF materials and their composites are also described.
Claims10
A method for preparing a catalyst, said method comprising:
- (a) providing a parent metal-organic framework (MOF), wherein the parent MOF comprises periodic repeats of a coordination complex comprising (i) an organic bridging ligand, wherein the organic bridging ligand is trimesic acid (BTC) or 2,2′-bipyridine-5,5′-dicarboxylate (dcbpy);
- and (ii) a metal-containing secondary building unit (SBU), wherein said metal-containing SBU comprises a metal oxo cluster comprising a metal ion M and one or more terminal or bridging OH or OH2 ligands, wherein the metal ion M is selected from a zirconium (Zr) ion, an iron (Fe) ion, a chromium (Cr) ion, and an aluminum (Al) ion;
- and
- (b) reacting the parent MOF with a silyl triflate to replace one or more of the one or more terminal or bridging OH or OH2 ligands with a triflate ligand.
Dependencies are inferred from the claim text.