Transdermal drug delivery patch and manufacturing method thereof
AssigneesPostech Academy-Industry Foundation, Shilla Industrial Co., Ltd.
InventorsGeunbae Lim, Jungho Lee, Byoungsun Choi, Hyeonsu Woo
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Abstract
A transdermal drug delivery patch according to an exemplary embodiment of the present invention includes: a flexible base layer; and a plurality of microneedle disposed at one surface of the base layer. Each of the plurality of microneedles includes a biodegradable polymer and a drug and has an empty space inside. Each of the plurality of microneedles is formed as a star-shaped pyramid including a plurality of protrusions extending in a radial direction, and a part between two protrusions adjacent along the circumferential direction among the plurality of protrusions is concave.
Claims11
A manufacturing method of a transdermal drug delivery patch, comprising:
- manufacturing a master mold including a transparent plate and a plurality of protruded parts disposed at one surface of the transparent plate and made of a star-shaped pyramid including a plurality of protrusions extending in a radial direction;
- manufacturing a mold including a plurality of recess portions having a shape corresponding to a plurality of protruded parts by using the master mold;
- and
- manufacturing a transdermal drug delivery patch including a base layer and a plurality of microneedles having a shape corresponding to a plurality of recess portions while having an empty space inside by using the mold, and a drug and a biodegradable polymer solution,
- wherein the empty space of each of the plurality of microneedles is a star-shaped pyramid including a plurality of protrusions extending in the radial direction.
Dependencies are inferred from the claim text.