In vivo positionable filtration devices and methods related thereto

A method for filtering one or more chemotherapeutic agents in blood flowing in a blood vessel within a patient, the method comprising:

• introducing a distal end of an elongate member carrying a filtering component into the blood vessel downstream from a target tissue site;
• expanding the filtering component within the blood vessel, the filtering component comprising a porous membrane including a proximal end and a distal end, the porous membrane expanding within the blood vessel such that the blood flowing through the blood vessel passes into the distal end through an interior of the filtering component and out the proximal end;
• and
• administering a chemotherapeutic agent of the one or more chemotherapeutic agents upstream from the target tissue site to direct flow of the chemotherapeutic agent to the target tissue site and then to the filtering component,
• wherein the filtering component comprises a filtration material disposed within the porous membrane configured to bind the chemotherapeutic agent as the blood flows through the interior of the filtering component,
• wherein the filtration material comprises a plurality of beads comprising a resin that binds or adsorbs the chemotherapeutic agent.

A method for filtering one or more chemotherapeutic agents in blood flowing in a blood vessel within a patient, the method comprising:

• introducing a distal end of an elongate member carrying a filtering component into the blood vessel downstream from a target tissue site;
• deploying the filtering component within the blood vessel, the filtering component comprising a porous membrane including a proximal end and a distal end and configured such that the blood flowing through the blood vessel passes through an interior of the filtering component;
• and
• administering a chemotherapeutic agent of the one or more chemotherapeutic agents upstream from the target tissue site to direct flow of the chemotherapeutic agent to the target tissue site and then to the filtering component,
• wherein the filtering component comprises a filtration material disposed within the porous membrane configured to bind or adsorb the chemotherapeutic agent as the blood flows through the interior of the filtering component,
• wherein the filtration material comprises a plurality of beads comprising a resin that traps or captures the chemotherapeutic agent.