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US 12,036,330 B2Granted
Tissue substitute multilayer matrix and uses thereof
AssigneeNurami Medical Ltd.
InventorsNora Nseir Manassa, Amir Bahar
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Abstract
Compositions-of-matter comprising a matrix made of one or more, preferably two or more elastic layers and one or more viscoelastic layer are disclosed. The compositions-of-matter are characterized by high water-impermeability and optionally by self-recovery. Processes of preparing the compositions-of-matter and uses thereof as tissue substitutes or for repairing damaged tissues are also disclosed.
Claims20
A composition-of-matter comprising a multi-layer matrix, said matrix comprising at least one layer of a viscoelastic polymeric material interposed between two or more layers of an elastic polymeric material, wherein:
- each of said two or more layers of said elastic polymeric material is in a form of a porous layer of polymeric fibers;
- a glass transition temperature of said viscoelastic polymeric material is below 0° C., and a melting point of said viscoelastic polymeric material is at a temperature below 45° C.;
- each of said polymeric fibers and said viscoelastic polymeric material independently comprises a biocompatible polymer;
- and
- wherein the viscoelastic polymeric material is in a form of a continuous polymeric film.
2 more elements
Dependencies are inferred from the claim text.