Bismuth-thiol compositions and methods for treating wounds
AssigneeMicrobion Corporation
InventorBrett Hugh James Baker
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Abstract
The invention relates to bismuth-thiol compounds and pharmaceutical preparations thereof. The invention further relates to methods for treating a topical wound, comprising administering to a subject in need thereof a therapeutically effective amount of a composition comprising a bismuth-thiol compound, wherein the composition is applied to the infection. Methods for treating microbial infections such as diabetic foot infections are also provided.
Claims23
A method for treating, managing, or healing a wound in a subject, comprising topically applying to the wound a therapeutically effective amount of a pharmaceutical composition comprising a bismuth-thiol (BT) compound suspended therein, wherein the composition comprises a plurality of microparticles comprising said BT compound, wherein the microparticles have a D90 of less than 2 a D50 of less than or equal to 0.72 μm to 1.3 μm, and/or a D10 of less than or equal to 0.33 μm to 0.70 μm.
Dependencies are inferred from the claim text.