Nanofiber composite membrane for guided bone regeneration, and manufacturing method therefor
AssigneeAmogreentech Co., Ltd.
InventorsChan Kim, Seung Hoon Lee, Seon Ho Jang, Ji Hyun Lee, Yun Mi So
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Abstract
Provided is a nanofiber composite membrane for guided bone regeneration, which includes: spinning a spinning solution by an electrospinning method to produce nanofibers; accumulating the nanofibers, to prepare a certain thickness of a nanofiber web; and drying and thermally calendering the nanofiber web to sterilize the nanofiber web, wherein the spinning solution contains a biocompatible plasticizer to maintain physical properties, flexibility and elasticity of the membrane, by suppressing an increase in brittleness in a sterilization treatment.
Claims7
A method of manufacturing a nanofiber composite membrane for guided bone regeneration, the method comprising:
- preparing a first spinning solution by mixing an electro-spinnable non-absorbent polymer material, a biocompatible plasticizer, and a solvent at a predetermined ratio;
- electro-spinning the first spinning solution to form a non-absorbent membrane made of first accumulated electro-spun nanofibers;
- prepare a second spinning solution by mixing an electro-spinnable non-absorbent polymer material, a biocompatible plasticizer, a guided bone regeneration material and a solvent at a predetermined ratio;
- electro-spinning the second spinning solution to form an absorbent membrane made of second accumulated electro-spun nanofibers;
- laminating the non-absorbent membrane and the absorbent membrane to form a composite membrane;
- and
- thermal calendaring the composite membrane having a certain thickness.
Dependencies are inferred from the claim text.