Back to results
US 12,030,986 B2Granted
Sustained release composition using biobased biodegradable hyperbranched polyesters
AssigneeCentral Michigan University
InventorsPatrick B. Smith, Bobby A. Howell, Cuiwei Zhang
Life of this patent
Estimating the term…
Abstract
The present invention provides a sustained release composition having hyperbranched polymers that are polyesters that are biobased and biodegradable, and that have at least one active ingredient, which composition delivers the active ingredient over time. These active ingredients can be a wide variety of compounds so long as they can covalently bind to the polymer or be encapsulated in the polymer in a manner that is released at the point of delivery, usually by acid hydrolysis or enzymatic bond scission.
Claims21
A composition comprising:
- a) a synthetic or natural biobased, biodegradable hyperbranched polyester (HB-PE), wherein the HB-PE is derived from a reaction between glycerol and a difunctional acid having two acid groups, wherein the molar ratio of alcohol groups to acid groups is greater than or equal to 2 or less than or equal to 0.5, wherein the extent of reaction of the minor component among the glycerol and difunctional acid is about unity;
- and
- b) an active ingredient covalently bonded to end groups of the HB-PE;
- wherein the composition is a viscous liquid.
1 more element
Dependencies are inferred from the claim text.