Perfusion systems and methods for monitoring tissue oxygenation and reducing limb ischemia
AssigneeTulyp Medical SAS
InventorsRichard H. Karas, Tim Lenihan, John McCarthy
Life of this patent
Estimating the term…
Abstract
Perfusion systems and methods are provided for increasing peripheral blood flow to reduce limb ischemia, in which an extracorporeal pump having a controller, and catheter/tubing set, employed alone or in conjunction with an interventional or circulatory assist device, withdraws blood from a patient's vasculature and reintroduces that blood at another location within the patient's vasculature at a controlled local pressure or flow rate, without interfering with operation of the interventional or circulatory assist device or surgical intervention.
Claims28
A perfusion system for use with an obstruction of antegrade flow to a patient's extremity due to thrombosis, trauma, or medical procedures/devices, the perfusion system comprising:
- an inlet cannula configured to be placed in a patient's vessel, the inlet cannula having a proximal end, a distal end and a lumen extending from the proximal end to the distal end, an inlet at the distal end, an outlet port and a hemostatic port disposed on the proximal end, wherein the inlet and the hemostatic port communicate with the lumen, and the hemostatic port is configured to permit an interventional or circulatory assist device to be inserted through the lumen to form an annulus that communicates with the outlet port;
- a return lumen having a proximal end and a distal end, the distal end of the return lumen configured to be placed in the patient's vessel downstream of the obstruction;
- an extracorporeal pump configured to be coupled to the outlet port of the inlet cannula and the proximal end of the return lumen;
- and
- a controller operatively coupled to the extracorporeal pump, the controller configured to cause the extracorporeal pump to enter a local pressure control mode wherein the extracorporeal pump is configured to draw blood through the inlet of the inlet cannula and to deliver blood at the distal end of the return lumen to perfuse the patient's extremity at a selected local pressure, independent of operation of the interventional or circulatory assist device.
A perfusion system comprising:
- at least one inlet cannula configured to be placed in a patient's vasculature, the at least one inlet cannula having a proximal end, a distal end and a lumen extending from the proximal end to the distal end, an inlet at the distal end, an outlet port disposed on the proximal end, wherein the inlet communicates with the lumen;
- at least one return lumen having a proximal end and a distal end, the distal end of the at least one return lumen configured to be placed in the patient's vasculature at one or more locations downstream of the inlet of the at least one inlet cannula;
- and
- an extracorporeal pump configured to be coupled to the outlet port of the at least one inlet cannula and the proximal end of the at least one return lumen;
- and
- a controller operatively coupled to the extracorporeal pump, the controller configured to cause the extracorporeal pump to enter a local pressure control mode wherein the extracorporeal pump is configured to draw blood through the inlet of the at least one inlet cannula and to deliver blood through the distal end of the at least one return lumen to perfuse the patient's extremity at a selected local pressure.
A perfusion system for returning blood accumulated within a patient's cavity to systemic circulation, the perfusion system comprising:
- an inlet cannula configured to be placed in a patient's cavity, the inlet cannula having a proximal end, a distal end and a lumen extending from the proximal end to the distal end, an inlet at the distal end, an outlet port disposed on the proximal end, and wherein the inlet communicates with the lumen;
- a return lumen having a proximal end and a distal end, the distal end of the return lumen configured to be placed in a patient's vessel;
- an extracorporeal pump configured to be coupled to the outlet port of the inlet cannula and the proximal end of the return lumen;
- and
- a controller operatively coupled to the extracorporeal pump, the controller configured to cause the extracorporeal pump to enter a local pressure control mode wherein the extracorporeal pump is configured to draw blood through the inlet of the inlet cannula and to deliver blood at the distal end of the return lumen to perfuse the patient's extremity at a selected local pressure.
Dependencies are inferred from the claim text.