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US 12,029,731 B2Granted
Acyl benzo[d]thiazol-2-amine and their methods of use
AssigneeBiohaven Therapeutics Ltd.
InventorsJeffery Claude Pelletier, Allen B. Reitz, Jay Edward Wrobel
Life of this patent
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Abstract
Disclosed are acyl benzo[d]thiazol-2-amines having a structure according to formula (I): including enantiomers, diastereomers, hydrates, solvates, pharmaceutically acceptable salts, and complexes thereof. The compounds may be useful for the treatment of various diseases including, for example, neurological disorders such as amyotrophic lateral sclerosis, bipolar disorder, treatment resistant and major depression, general anxiety disorder, and cancers such as melanoma, breast cancer, brain cancer, and prostate cancer.
Claims3
A compound having a structure according to formula (IX):
- including pharmaceutically acceptable salts thereof, wherein:
- R1, R2 and R3 are each independently hydrogen or halogen;
- R4 is hydrogen;
- R14a and R14b are hydrogen;
- R15 is C1-C6 alkyl;
- R17a and R17b are hydrogen;
- R19a is C1-C6 alkyl;
- and
- R19b is hydrogen.
6 more elements
Dependencies are inferred from the claim text.