Sample injection for liquid chromatography using split solvent flow

A fluidic network for chromatographic sample dilution during injection, comprising:

• a restriction valve having a first port, a second port, a plurality of fluidic nodes, and a movable valve channel having a first end fluidically coupled to the second port and having a second end configured to couple to a selected one of the fluidic nodes, wherein one of the first and second ports is an inlet port and the other one of the first and second ports is an outlet port;
• a plurality of flow restrictors, each flow restrictor having a first end coupled to one of the fluidic nodes and a second end to another one of the fluidic nodes, the flow restrictors arranged to form a serial path defined from a first one of the flow restrictors to a last one of the flow restrictors, wherein a fluidic path to conduct a liquid is defined between the first port and the second port and wherein the flow restrictors in the fluidic path are determined according to which one of the fluidic nodes is coupled to the second port;
• an injection valve having a plurality of injection valve ports, wherein one of the injection valve ports is an inlet port and another one of the injection valve ports is an outlet port, wherein the outlet port of the restriction valve is in fluidic communication with the inlet port of the injection valve;
• a first flow splitter comprising an inlet port, a first outlet port in fluidic communication with the inlet port of the restriction valve, and a second outlet port;
• and
• a first flow combiner having a first inlet port coupled to the second outlet port of the first flow splitter, a second inlet port, and an outlet port.