Genetic testing device
AssigneeHc Bio-Engineering (Chengdu) Co., Ltd.
InventorsJian Chen, Dejiang Zhou, Jie Li
Life of this patent
Estimating the term…
Abstract
A genetic testing device includes a safety cabinet, a gas flow control system, a first treatment module configured to treat an amplification reagent and a polymerase chain reaction (PCR) plate, a second treatment module configured to treat a reagent, a tip, and a gene sample, a sample injection module configured to inject an amplification reagent into a microwell of a PCR plate, a purification treatment module configured to treat a gene sample, an amplification detection module for gene amplification and detection, a heat sealer configured to seal a PCR plate, a material delivery module A, a material delivery module B, and a material delivery module C.
Claims20
A genetic testing device, comprising:
- a safety cabinet, wherein the safety cabinet is divided into an upper part and a lower part that are isolated from each other, and the upper part and the lower part of the safety cabinet each are divided into three mounting chambers that are isolated from one another;
- the three mounting chambers of the upper part are a first mounting chamber A, a first mounting chamber B, and a first mounting chamber C, and the three mounting chambers of the lower part are a second mounting chamber A, a second mounting chamber B, and a second mounting chamber C;
- and
- a first switch door assembly A is provided between the first mounting chamber A and the second mounting chamber A, a first switch door assembly B is provided between the first mounting chamber B and the second mounting chamber B, a first switch door assembly C is provided between the first mounting chamber C and the second mounting chamber C, a second switch door assembly A is provided between the second mounting chamber A and the second mounting chamber B, and a second switch door assembly B is provided between the second mounting chamber B and the second mounting chamber C;
- a gas flow control system configured to control gas pressure conditions of the first mounting chamber A, the first mounting chamber B, and the first mounting chamber C;
- a first treatment module configured to treat an amplification reagent and a polymerase chain reaction (PCR) plate;
- a second treatment module configured to treat a reagent, a tip, and a gene sample;
- a sample injection module configured to inject the amplification reagent into a microwell of the PCR plate;
- a purification treatment module configured to treat the gene sample;
- an amplification detection module for gene amplification and detection;
- a heat sealer configured to seal the PCR plate;
- a material delivery module A;
- a material delivery module B;
- and
- a material delivery module C, wherein the sample injection module and the first treatment module are arranged in the first mounting chamber A, the purification treatment module, the second treatment module, and the heat sealer are arranged in the first mounting chamber B, the amplification detection module is arranged in the first mounting chamber C, and the material delivery module A, the material delivery module B, and the material delivery module C are arranged in the second mounting chamber A, the second mounting chamber B, and the second mounting chamber C, respectively;
- the material delivery module A, the material delivery module B, and the material delivery module C are located below the sample injection module, the purification treatment module, and the amplification detection module, respectively;
- and
- during delivery, the sample injection module drives the PCR plate with the amplification reagent to pass through the first switch door assembly A and reach a transferring function end of the material delivery module A;
- when the material delivery module A delivers the PCR plate to the second switch door assembly A, the PCR plate is placed at a transferring function end of the material delivery module B;
- when the material delivery module B delivers the PCR plate to the first switch door assembly B, the PCR plate enters the first mounting chamber B through the purification treatment module, and a purified gene sample is added to the PCR plate;
- the PCR plate is hot-sealed by the heat sealer;
- the PCR plate with the gene sample is placed at the transferring function end of the material delivery module B through the purification treatment module and the first switch door assembly B;
- when the material delivery module B delivers the PCR plate to the second switch door assembly B, the PCR plate is placed at a transferring function end of the material delivery module C;
- and when the material delivery module C delivers the PCR plate to the first switch door assembly C, the PCR plate enters the first mounting chamber C through the purification treatment module, and the gene sample in the PCR plate is subjected to genetic testing by the amplification detection module;
- the sample injection module, the purification treatment module, and the amplification detection module each comprise a transfer assembly, a gripper A configured to transfer the PCR plate, and a gripper control member A configured to control an open or close of the gripper A, and the sample injection module and the purification treatment module each further comprise a pipette assembly A configured to transfer a liquid;
- the transfer assembly comprises:
- an X-direction moving component for X-direction movement, wherein the X-direction moving component comprises a motor A, a driving pulley A, a driven pulley A, a drive belt A, and a mounting plate A, the mounting plate A is fixedly connected to the drive belt A, a rotating shaft of the motor A is fixedly connected to a rotation center of the driving pulley A, and the driving pulley A and the driven pulley A are in a transmission connection through the drive belt A;
- a Y-direction moving component for Y-direction movement, wherein the Y-direction moving component comprises a motor B, a driving pulley B, a driven pulley B, a drive belt B, and a mounting plate B, the mounting plate B is fixedly connected to the drive belt B, a rotating shaft of the motor B is fixedly connected to a rotation center of the driving pulley B, and the driving pulley B and the driven pulley B are in a transmission connection through the drive belt B;
- and
- a Z-direction moving component for Z-direction movement, wherein the Z-direction moving component comprises a motor C, a lead screw nut mechanism A, and a mounting plate C, a rotating shaft of the motor C is fixedly connected to a lead screw A of the lead screw nut mechanism A, the mounting plate C is fixedly connected to a nut A of the lead screw nut mechanism A, and the gripper control member A and the pipette assembly A both are fixedly arranged on the mounting plate C;
- the X-direction moving components of the sample injection module and the amplification detection module are arranged on the mounting plate B, and the Z-direction moving components of the sample injection module and the amplification detection module are fixedly arranged on the mounting plate A;
- and
- the Y-direction moving component of the purification treatment module is arranged on the mounting plate A, and the Z-direction moving component of the purification treatment module is fixedly arranged on the mounting plate B.
Dependencies are inferred from the claim text.