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US 12,023,665 B2Granted
Devices and methods for modifying optical properties
AssigneePfizer Inc.
InventorsFrank B. Myers, III, Debkishore Mitra, John Robert Waldeisen, Ivan Krastev Dimov
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Abstract
Devices and methods for modifying optical properties of biological samples or aspects thereof are provided. The subject methods include generating a reaction product with a device and reacting the reaction product to sufficiently modify an optical property to allow detection of the modified optical property.
Claims83
A biological sample assay optical property modifying device, the device comprising:
- a) a sample receiving cartridge comprising i) a sample inlet, ii) reaction chambers each comprising an optical property modifying reagent, and iii) one or more conduits operatively connecting the reaction chambers with the sample inlet;
- b) a substrate comprising:
- i) a heating element;
- and
- ii) a power source operatively coupled to the heating element;
- and
- c) an adhesive layer operatively connecting the sample receiving cartridge and the substrate, wherein the adhesive layer forms a wall of each of the reaction chambers, and wherein the adhesive layer comprises one or more adhesive.
4 more elements
Dependencies are inferred from the claim text.