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US 12,023,380 B2Granted
Combined cancer therapy with immune checkpoint modulators and fermentation products by symbiotic microbiota
AssigneeMicrobio Co., Ltd.
InventorKung-Ming Lu
Life of this patent
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Abstract
Combined therapy of cancer using an immune check point modulators (e.g., an immune checkpoint inhibitor) and a fermented product, which may be prepared using symbiotic microbiota.
Claims28
A method for treating cancer, comprising:
- (i) administering to a subject in need thereof an effective amount of an immune checkpoint inhibitor, which is an inhibitor of PD-1;
- and
- (ii) administering to the subject a fermented composition, which comprises multiple metabolites that are generated via fermentation of a legume plant or a portion thereby by a mixture of microorganisms;
- wherein the legume plant is soybean, and wherein the mixture of microorganisms comprise a yeast and a lactobacillus.
1 more element
A method for treating cancer, comprising administering to a subject in need thereof an effective amount of a fermented composition, which comprises multiple metabolites that are generated via fermentation of a legume plant or a portion thereof by a mixture of microorganisms, which comprise a yeast and a lactobacillus;
- wherein the legume plant is soybean, and wherein the subject has undergone or is undergoing an anti-cancer therapy that involves an immune checkpoint inhibitor, which is an inhibitor of PD-1.
Dependencies are inferred from the claim text.