Method for analyzing isoaspartic acid and mass spectrometer
AssigneesShimadzu Corporation, National Institute of Advanced Industrial Science and Technology
InventorsHidenori Takahashi, Daiki Asakawa
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Abstract
In a method for analyzing isoaspartic acid by dissociating precursor ions derived from a sample component and generating and analyzing product ions, the method includes: generating product ions by irradiating the precursor ions with hydrogen radicals or radicals having oxidizing ability to dissociate the precursor ions; separating and detecting the product ions according to a mass-to-charge ratio; and specifying product ions derived from isoaspartic acid based on a mass-to-charge ratio of the product ions.
Claims8
A method for analyzing isoaspartic acid by dissociating precursor ions derived from a sample component and generating and analyzing product ions, the method comprising:
- generating product ions by irradiating the precursor ions with hydrogen radicals or radicals having oxidizing ability to dissociate the precursor ions;
- separating and detecting the product ions according to a mass-to-charge ratio;
- and
- specifying product ions derived from isoaspartic acid based on a mass-to-charge ratio of the product ions.
A mass spectrometer for analyzing isoaspartic acid by dissociating precursor ions derived from a sample component and generating and analyzing product ions, the mass spectrometer comprising:
- a reaction chamber into which the precursor ions are introduced;
- a radical generation unit configured to generate a hydrogen radical or a radical having oxidizing ability;
- a radical irradiation unit configured to irradiate an inside of the reaction chamber with radicals generated by the radical generation unit;
- a separation and detection unit configured to separate and detect product ions generated by dissociation of the precursor ions by reaction with the radicals according to a mass-to-charge ratio;
- and
- a product ion specifying unit configured to specify product ions derived from isoaspartic acid on a basis of a mass-to-charge ratio of the product ions.
Dependencies are inferred from the claim text.