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US 12,018,291 B2Granted
Compositions and methods for antigen targeting to CD180
AssigneeUniversity of Washington
InventorsEdward Clark, Jay Wesley Chaplin
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Abstract
The present invention provides compositions of CD 180 targeting molecules coupled to heterologous antigens, and their use in treating and/or limiting disease.
Claims20
An isolated nucleic acid encoding a fusion protein comprising:
- (a) an antibody that selectively binds CD180 or an antigen binding fragment thereof;
- and
- (b) a heterologous polypeptide antigen.
Dependencies are inferred from the claim text.