Annelid haemoglobin lyophilisation process

A process for storing at least one extracellular hemoglobin, globin protomer or globin of annelids, comprising:

• i) mixing a solution comprising at least one extracellular hemoglobin selected from the extracellular hemoglobin of Arenicola marina and the extracellular hemoglobin of Nereis, at least trehalose, 1 to 50 g/l of at least one polyol selected from mannitol and sorbitol, and at least ascorbic acid, wherein the solution does not comprise any tris-acetate buffer and any cofactor;
• ii) freezing the mixture at a temperature of between −10° C. and −100° C. for a time of at least 24 h;
• iii) sublimating the frozen mixture for at least 2 h, under vacuum;
• iv) drying the sublimated mixture until a powder is obtained, so as to obtain a lyophilizate;
• and
• v) storing the lyophilizate in a container.