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US 12,016,933 B2Granted
Method for stimulating axonal regeneration
AssigneeThe Hong Kong University of Science and Technology
InventorsChao Yang, Xu Wang, Kai Liu
Life of this patent
Estimating the term…
Abstract
A method of promoting axonal regeneration can include directing neuronal lipid synthesis away from triglyceride synthesis and toward phospholipid synthesis. The method can include administering to the patient a therapeutically effective amount of an inhibitor compound selected from the group consisting of a Lipin-1 inhibitor, a diglyceride acyltransferase inhibitor, and combinations thereof or administering a gene editing therapy to the patient that reduces expression of LIPIN1 or a diglyceride acyltransferase gene.
Claims5
A method of promoting axon regeneration in a patient, comprising:
- administering a therapeutically effective amount of an inhibitor compound to the patient, wherein
- the inhibitor compound is a diglyceride acyltransferase inhibitor which comprises at least one of the following inhibitor compounds:
Dependencies are inferred from the claim text.