Contact imaging of standards with illumination
AssigneeBio-Rad Laboratories, Inc.
InventorsStephen Swihart, Evan Thrush, Carl Marlowe, Kenneth Oh, Michael Griffin
Life of this patent
Estimating the term…
Abstract
Systems and methods for contact imaging of stands with illumination are disclosed herein. A contact imaging system can include a contact imager. The contact imager can include a housing having a base and a lid. The lid can have a closed position against the base and an open position. The contact imager can include a contact area image sensor. The lid can shield the contact area image sensor from ambient light when the lid is in the closed position. The contact imager can include an illuminator that can illuminate at least a portion of a blot on the contact area image sensor when the lid is in the closed position.
Claims22
A contact imaging system, comprising:
- a contact imager comprising:
- a housing having a base and a lid, the lid having a closed position against the base and having an open position;
- and
- a contact area image sensor located in the base, wherein the lid shields the contact area image sensor from ambient light when the lid is in the closed position;
- and
- an illuminator configured to illuminate at least a portion of a blot on the contact area image sensor when the lid is in the closed position.
A method of imaging a sample, the method comprising:
- placing a resolved sample on a contact area image sensor, the contact area image sensor located in a base of a contact imager;
- moving a lid of the contact area image sensor to a closed position, wherein in the closed position, the lid prevents ambient light from reaching the contact area image sensor;
- generating, with the contact area image sensor, a first image of first sample features, wherein the first image is of the resolved sample and is generated with light emitted by the sample;
- illuminating the resolved sample with an illuminator of the contact imager, the illuminator configured to illuminate at least a portion of the contact area image sensor when the lid is in the closed position;
- and
- generating, with the contact area image sensor, a second image of second sample features while the lid is in the closed position, the second sample features comprising standards, wherein the second image of the second sample features is generated while the resolved sample is illuminated.
Dependencies are inferred from the claim text.