US 12,012,614 B2 · Inducer for inducing a mesenchymal stem cell to differentiate into an islet cell

Abstract

The present invention belongs to the field of biomedicine, and relates to an inducer for inducing a mesenchymal stem cell to differentiate into an islet cell. An inducer for inducing a mesenchymal stem cell to differentiate into an islet cell consisted of the following components: GLP-1, parathyroid hormone, paracetamol, rapamycin, icariin, trametinib, EPO and VEGF. Each component in a inducer for inducing a mesenchymal stem cell to differentiate into an islet cell of the present invention is safe and non-toxic, requiring fewer steps and short time to induce differentiation, with high induction efficiency.

Claims3

Dependent claims

An inducer for inducing a human umbilical cord mesenchymal stem cell to differentiate into an islet cell, wherein the inducer is a liquid consisting of the following components:

GLP-1, parathyroid hormone, paracetamol, rapamycin, icariin, trametinib, EPO, and VEGF;
wherein the mass concentration of each component is as follows:
GLP-1 20-40 mg/L, parathyroid hormone 6-12 mg/L, paracetamol 2-8 mg/L, rapamycin 2-8 mg/L, icariin 2-8 mg/L, trametinib 0.3-0.6 mg/L, EPO 2-4 μg/L, and VEGF 2-4 μg/L.

Dependencies are inferred from the claim text.

Inducer for inducing a mesenchymal stem cell to differentiate into an islet cell

Life of this patent

Inducer for inducing a mesenchymal stem cell to differentiate into an islet cell

Life of this patent

Abstract

Claims3