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US 12,012,238 B2Granted
Packaging solutions
AssigneeBausch + Lomb Ireland Limited
InventorsAlok K. Awasthi, Jade J. Russell, Mark R. Mis
Life of this patent
Estimating the term…
Abstract
A packaging system for the storage of an ophthalmic device is disclosed. The packaging system includes a sealed container containing one or more unused ophthalmic devices immersed in an aqueous packaging solution that includes ectoine or an ophthalmologically acceptable ectoine derivative. The aqueous packaging solution has an osmolality of at least about 150 mOsm/kg, a pH of about 6 to about 9 and is sterilized.
Claims22
A packaging system, comprising:
- a sealed container containing one or more unused ophthalmic devices immersed in an aqueous packaging solution comprising ectoine or an ophthalmologically acceptable ectoine derivative and a modified glycosaminoglycan;
- wherein the aqueous packaging solution has an osmolality of at least about 150 mOsm/kg, a pH of about 6 to about 9 and is sterilized;
- wherein the modified glycosaminoglycan comprises a reaction product of a first glycosaminoglycan, a second glycosaminoglycan, and a first crosslinking agent, wherein the first glycosaminoglycan is different than the second glycosaminoglycan.
A packaging system, comprising:
- a sealed container containing one or more unused ophthalmic devices immersed in an aqueous packaging solution comprising ectoine or an ophthalmologically acceptable ectoine derivative and a modified glycosaminoglycan;
- wherein the aqueous packaging solution has an osmolality of at least about 150 mOsm/kg, a pH of about 6 to about 9 and is sterilized;
- wherein the modified glycosaminoglycan comprises a glycophospholipid polymer comprising a reaction product of one or more glycosaminoglycans and one or more phospholipids.
A packaging system, comprising:
- a sealed container containing one or more unused ophthalmic devices immersed in an aqueous packaging solution comprising ectoine or an ophthalmologically acceptable ectoine derivative and a modified glycosaminoglycan;
- wherein the aqueous packaging solution has an osmolality of at least about 150 mOsm/kg, a pH of about 6 to about 9 and is sterilized;
- wherein the modified glycosaminoglycan comprises a grafted glycosaminoglycan polymer comprising a glycosaminoglycan having a polymer backbone and one or more side chains comprising a polyalkylene glycol-containing residue grafted onto the polymer backbone.
A packaging system, comprising:
- a sealed container containing one or more unused ophthalmic devices immersed in an aqueous packaging solution comprising ectoine or an ophthalmologically acceptable ectoine derivative and a modified glycosaminoglycan;
- wherein the aqueous packaging solution has an osmolality of at least about 150 mOsm/kg, a pH of about 6 to about 9 and is sterilized;
- wherein the modified glycosaminoglycan comprises a reaction product of (a) a grafted glycosaminoglycan polymer comprising a glycosaminoglycan having a polymer backbone and one or more side chains comprising a polyalkylene glycol-containing residue grafted onto the polymer backbone;
- and (b) one or more first crosslinking agents.
1 more element
Dependencies are inferred from the claim text.