Treatments of oxidative stress conditions
AssigneeUniversity of Vermont and State Agricultural College
InventorsYvonne M. Janssen-Heininger, Vikas Anathy
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Abstract
The present invention generally relates to systems and methods for treating certain oxidative stress conditions. In one aspect, compositions and methods of the invention can be used to treat a subject having an oxidative stress condition, for example, a subject having pulmonary fibrosis. In some embodiments, an inhibitor of ERp57 (for example, thiomuscimol) and/or an inhibitor of GSTP (for example, TLK-199) may be used to treat the subject. Also provided in certain aspects of the present invention are kits for such therapies, methods for promoting such therapies, and the like.
Claims8
A method of treating idiopathic pulmonary fibrosis, the method comprising:
- administering, to a subject having idiopathic pulmonary fibrosis, a composition comprising an effective amount of an inhibitor of GSTP, wherein the inhibitor comprises gamma-glutamyl-S-(benzyl)cysteinyl-R-phenyl glycine diethyl ester.
Dependencies are inferred from the claim text.