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US 12,011,214 B2Granted
Systems, methods, and devices for monitoring and treatment of tissues within and/or through a lumen wall
AssigneeAutonomix Medical, Inc.
InventorsLandy Toth, Roy Martin
Life of this patent
Estimating the term…
Abstract
A system for controlled sympathectomy procedures is disclosed. A system for controlled micro ablation procedures is disclosed. Methods for performing a controlled surgical procedure are disclosed. A system for performing controlled surgical procedures in a minimally invasive manner is disclosed. Systems and methods for accessing target tissues as part of a neuromodulation procedure from within a lumen are disclosed.
Claims20
A tool comprising:
- an elongate member comprising a distal tip and a control end, the elongate member configured to extend from an entry site on a body into a lumen within the body;
- one or more probes coupled with the distal tip of the elongate member, the one or more probes being configured for deployment from the elongate member responsive to actuation at the control end;
- and
- a controller coupled with the one or more probes, the controller comprising a radiofrequency generator, a signal monitoring block, and a signal conditioning unit;
- wherein a given one of the probes comprises a probe tip configured to penetrate at least one of into and through a wall of the lumen upon deployment of the given probe from the elongate member;
- and
- wherein the given probe comprises two or more electrodes configured to at least one of monitor and alter electrophysiological activity in a vicinity of the lumen;
- wherein the elongate member comprises a guidewire and a helical catheter from which the one or more probes are advanced towards target tissues in the vicinity of the lumen;
- wherein the guidewire has a stiffer shank than the helical catheter such that when the helical catheter is advanced over the guidewire the helical catheter takes on a substantially straight form and when the guidewire is retracted the helical catheter takes on a helical shape that biases against the wall of the lumen;
- wherein the controller is configured:
- to utilize the radiofrequency generator to deliver a stimulating train of one or more pulses to one or more tissue sites in the vicinity of the lumen via the one or more probes;
- to utilize the signal monitoring block to monitor one or more electrical characteristics of the stimulating train of pulses, the monitored one or more electrical characteristics of the stimulating train of pulses comprises electrode-to-electrode impedance values of the two or more electrodes of the given probe;
- and
- to utilize the signal conditioning unit to determine, based at least in part on the monitored one or more electrical characteristics of the stimulating train of pulses and the monitored electrophysiological activity in the vicinity of the lumen, feedback for adjusting the stimulating train of one or more pulses delivered by the radiofrequency generator to the one or more tissue sites in the vicinity of the lumen via the one or more probes.
11 more elements
A system comprising:
- a tool comprising an elongate member and one or more probes coupled to a distal tip of the elongate member and configured for deployment from the elongate member responsive to actuation at a control end of the elongate member, a given one of the probes comprising a probe tip configured to penetrate at least one of into and through a wall of the lumen upon deployment of the given probe from the elongate member, the given probe comprising two or more electrodes;
- and
- a control unit configured to exchange signaling with the control end of the elongate member to direct the one or more electrodes of the given probe to at least one of monitor and alter electrophysiological activity in a vicinity of the lumen, the control unit comprising a radiofrequency generator, a signal monitoring block, and a signal conditioning unit;
- wherein the elongate member comprises a guidewire and a helical catheter from which the one or more probes are advanced towards target tissues in the vicinity of the lumen;
- and
- wherein the guidewire has a stiffer shank than the helical catheter such that when the helical catheter is advanced over the guidewire the helical catheter takes on a substantially straight form and when the guidewire is retracted the helical catheter takes on a helical shape that biases against the wall of the lumen;
- and
- wherein the control unit is configured:
- to utilize the radiofrequency generator to deliver a stimulating train of one or more pulses to one or more tissue sites in the vicinity of the lumen via the one or more probes;
- to utilize the signal monitoring block to monitor one or more electrical characteristics of the stimulating train of pulses, the monitored one or more electrical characteristics of the stimulating train of pulses comprises electrode-to-electrode impedance values of the two or more electrodes of the given probe;
- and
- to utilize the signal conditioning unit to determine, based at least in part on the monitored one or more electrical characteristics of the stimulating train of pulses and the monitored electrophysiological activity in the vicinity of the lumen, feedback for adjusting the stimulating train of one or more pulses delivered by the radiofrequency generator to the one or more tissue sites in the vicinity of the lumen via the one or more probes.
9 more elements
Dependencies are inferred from the claim text.