# US 12,007,543 B2 · Optical system

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- Number: US 12,007,543 B2
- Document ID: US12007543B2
- Status: Granted
- Kind: B2
- Application number: 18/006,219
- Filed: 2021-07-21
- Published: 2023-09-07
- Granted: 2024-06-11
- Earliest claimed: 2020-07-22
- Assignees: Hochschule Emden/Leer
- Applicants: Hochschule Emden/Leer
- Inventors: James Napier; Walter Neu
- Web page: https://patentgrep.com/patent/US12007543B2

## CPC

- G02B 21/0032: {Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers (G02B21/0036 - G02B21/008; means for illumination of specimens in general G02B21/06)}
- G02B 21/361: {Optical details, e.g. image relay to the camera or image sensor (G02B21/364 takes precedence; illumination details G02B21/06 and subgroups)}
- G01J 1/0411: {using focussing or collimating elements, i.e. lenses or mirrors; Aberration correction}
- G01J 1/0425: {using optical fibers}
- G02B 21/008: {Details of detection or image processing, including general computer control}
- G02B 27/1013: {for colour or multispectral image sensors, e.g. splitting an image into monochromatic image components on respective sensors (spectral imaging systems G01J)}
- G02B 27/141: {using dichroic mirrors}
- G02B 27/145: {having sequential partially reflecting surfaces}
- G02B 27/146: {with a tree or branched structure}
- G02B 21/0056: {based on optical coherence, e.g. phase-contrast arrangements, interference arrangements}
- G02B 21/0076: {arrangements using fluorescence or luminescence}
- G02B 21/33: Immersion oils {, or microscope systems or objectives for use with immersion fluids}
- G02B 26/08: for controlling the direction of light (in light guides G02B6/35)
- G02B: OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G01J: MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY (light sources F21, H01J, H01K, H05B; investigating properties of materials by optical means G01N)

## Abstract

This relates to an optical system for detecting radiation from a measuring area, comprising at least one radiation source for generating radiation along an excitation beam path which guides radiation from the radiation source to the measuring area, and comprising a detection beam path which guides radiation from the measuring area to at least a first and a second detector, wherein along the detection beam path, exactly one tube lens having a first end and an opposite second end, a first beam splitter, a first detector in the reflection direction of the first beam splitter, and a second detector in the transmission direction of the first beam splitter are arranged in succession, wherein the first detector has a first detection surface and the second detector has a second detection surface which is spaced from the first detection surface, and the first and second detection surfaces are arranged along the detection beam path at the same distance from the second end of the tube lens.

## Claims

### Claim 1

An optical system for detecting radiation from a measuring area, comprising:
at least one radiation source arranged to radiation along an excitation beam path that guides radiation from the radiation source to the measuring area;
a detection beam path that guides radiation from the measuring area to at least a first and a second detector; the detection beam path comprising in succession exactly one tube lens comprising a first end and an opposite second end, a first beam splitter, a first detector in a reflection direction of the first beam splitter and a second detector in a transmission direction of the first beam splitter;
wherein the first detector comprises a first detection surface and the second detector comprises a second detection surface spaced from the first detection surface;
wherein the first and second detection surfaces are arranged along the detection beam path at the same distance (f) from the second end of the tube lens, the system further comprising a third detector comprising a third detection surface spaced from the first and second detection surfaces, the third detection surface being affair arranged along the detection beam path at the same distance (f) from the second end of the tube lens: and
a second beams splitter is arranged along the detection beam path downstream of the first beam splitter and in a transmission or reflection direction in which the third. detector is arranged.

### Claim 2 (depends on 1)

The optical system according to claim 1, wherein the distance (f) is equal to a working distance of the exactly one tube lens.

### Claim 3 (depends on 1)

The optical system according claim 1, wherein no beam splitter is arranged in the detection beam path upstream of the exactly one tube lens.

### Claim 4 (depends on 1)

The optical system according to claim 1, wherein no optical elements other than lenses are arranged in the detection beam path upstream of the exactly one tube lens.

### Claim 5 (depends on 1)

The optical system according to claim 1, wherein the radiation generated by the radiation source is guided in the excitation beam path through the exactly one tube lens.

### Claim 6 (depends on 1)

The system according to claim 1, wherein the tube lens, the first beam splitter, and the first detector are arranged such that a sample can be arranged at a fixed distance in front of the exactly one tube lens in the common housing.

### Claim 7 (depends on 1)

The optical system according to claim 1, wherein the detection beam path is at least sectionally filled with liquid.

### Claim 8 (depends on 1)

The optical system according to claim 1, wherein the detection beam path is at least sectionally formed by a fiber.

### Claim 9 (depends on 1)

The optical system according to claim 1, comprising a lens array as an objective in the detection beam path upstream of the exactly one tube lens, the lenses of the objective being mounted movably or fixedly with respect to the exactly one tube lens, wherein the optical system in its detection beam path has an infinity region in the region between the first end of the objective and the second end of the tube lens.

### Claim 10 (depends on 1)

The optical system according to claim 1, wherein the first beam splitter comprises an optical switch configured to control the redirection or transmission of radiation depending on a predetermined signal.

### Claim 11 (depends on 1)

The optical system according to claim 1, comprising optical elements configured for redirecting and/or reflecting and/or guiding radiation upstream or downstream of the first, second and/or third detection surfaces.

### Claim 12

An optical system for detecting radiation from a measuring area, comprising:
at least one radiation source arranged to radiation along an excitation beam path that guides radiation from the radiation source to the measuring area;
a detection beam path that guides radiation from the measuring area to at least a first and a second detector; the detection beam comprising in succession exactly one tube lens comprising a first end and an opposite second end, a first beam splitter, a first detector in a reflection direction of the first beam splitter and a second detector in a transmission direction of the first beam splitter;
wherein the first detector comprises a first detection surface and the second detector comprises a second detection surface spaced from the first detection surface;
wherein the first and second detection surfaces are arranged along the detection beam at the same distance (f) from the second end of the tube lens, wherein the radiation source of the optical system is controllably movable along a first axis and at an angle thereto along a second axis starting from a zero point, wherein the two axes span a plane at right angles to the excitation beam path;
wherein a beam splitter is configured to redirect the radiation towards an XY detection arm;
wherein the XY detection arm comprises a beam splitter in the reflection direction and transmission direction of which one detector each for the radiation of the radiation source is arranged, wherein the one detector) is configured to determine the location of the radiation incident thereon and to determine therefrom the displacement relative to the zero point along the first axis, and wherein the other detector is configured to determine the location of the radiation incident thereon and to determine therefrom the displacement relative to the zero point along the second axis,
and the optical system comprises a control device configured to move the radiation source along the first and/or second axis towards the zero point in dependence on the determined signal of the two detectors.

### Claim 13 (depends on 12)

The optical system according to claim 12, comprising a second XY detection arm comprising at least one detector configured to determine the location of radiation incident thereon and to determine therefrom the displacement relative to a zero point along a first and/or second axis, and a control device configured to move the radiation source of a second optical system in dependence on the determined signal of the at least one detector of the second XY detection arm along a first and/or second axis towards a zero point.