# US 12,007,371 B2 · Removable seal device for fluidic coupling > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 12,007,371 B2 - Document ID: US12007371B2 - Status: Granted - Kind: B2 - Application number: 16/822,769 - Filed: 2020-03-18 - Published: 2020-09-24 - Granted: 2024-06-11 - Earliest claimed: 2019-03-19 - Assignees: Waters Technologies Corporation - Applicants: Waters Technologies Corporation - Inventors: Sylvain Gilles Cormier; Joseph D. Antocci; Wade P. Leveille, Sr. - Web page: https://patentgrep.com/patent/US12007371B2 ## CPC - G01N 30/6026: {Fluid seals} - F16L 15/04: with additional sealings - G01N 2030/027: {Liquid chromatography} - G01N 2030/202: {rotary valves} - G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q) - F16L: PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL ## Abstract A removable seal device for fluidic coupling includes a seal body extending between a first end and a second end, the seal body including an inner channel configured to receive a flow of a fluid. The first end of the seal body includes a first sealing surface configured to create a first seal with a fitting sealing surface of a receiver fitting, and the seal body includes a second sealing surface configured to create a second seal with an end of a fluidic tube. The removable seal is configured to be removably secured to at least one of the fluidic tube, a support feature fixed to the fluidic tube, and a compression screw, such that untightening of the compression screw from the receiver fitting causes the removable seal device to be removed from the receiver fitting. ## Claims ### Claim 1 A removable seal device for fluidic coupling for use in a chromatography system comprising: a seal body extending between a first end and a second end, the seal body including an inner channel configured to receive a flow of a fluid, wherein the first end of the seal body includes a first sealing surface configured to create a first seal with a fitting sealing surface of a receiver fitting, and wherein the seal body incudes a second sealing surface configured to create a second seal with an end of a fluidic tube, wherein the removable seal is configured to be removably secured to at least one of the fluidic tube, a support feature fixed to the fluidic tube, and a compression screw, such that untightening of the compression screw from the receiver fitting causes the removable seal device to be removed from the receiver fitting, wherein the seal body includes a cylindrical portion extending from the first end, and a conical portion extending from the cylindrical portion and expanding in diameter as the conical portion extends from the cylindrical portion, wherein the cylindrical portion includes an internal bore dimensioned to receive the end of the fluidic tube and a length of the fluidic tube, the seal body further including an internal surface within at least one of the conical portion and a cylindrical extended portion of the conical portion, the internal surface including threads configured to facilitate the removably securing to the at least one of the fluidic tube, the support feature fixed to the fluidic tube, and the compression screw; and a metallic support sleeve surrounding the cylindrical portion configured to support the seal body. ### Claim 2 A fluidic coupling for use in a chromatography system comprising: a fluidic tube including an end surface, wherein the fluidic tube includes a support feature fixed to the fluidic tube proximate the end surface; a compression screw having a main body extending along an axis from a first end to a second end, the compression screw including a compression screw threaded portion configured to engage with internal threads of a receiver fitting, the compression screw including an opening extending from the first end to the second end along the axis, wherein the fluidic tube is configured to extend through the opening; and a removable seal device for fluidic coupling including a seal body extending between a first end and a second end, the seal body including an inner channel configured to receive a flow of a fluid, wherein the first end of the seal body includes a first sealing surface configured to create a first seal with a fitting sealing surface of a receiver fitting, and wherein the seal body incudes a second sealing surface configured to create a second seal with an end of a fluidic tube, wherein the removable seal device is configured to be removably secured to at least one of the fluidic tube, the support feature fixed to the fluidic tube, and a compression screw, such that untightening of the compression screw from the receiver fitting causes the removable seal device to be removed from the receiver fitting, wherein the support feature has a greater diameter than the fluidic tube, the support feature configured to abut the first end of the compression screw, the support feature including a support feature threaded portion, and wherein the threads of the internal surface of the seal body are configured to engage the threaded portion of the removable seal device, wherein the seal body includes a cylindrical portion extending from the first end, and a conical portion extending from the cylindrical portion and expanding in diameter as the conical portion extends from the cylindrical portion, wherein the cylindrical portion includes an internal bore dimensioned to receive the end of the fluidic tube and a length of the fluidic tube, the seal body further including an internal surface within at least one of the conical portion and a cylindrical extended portion of the conical portion, the internal surface including threads configured to facilitate the removably securing to the at least one of the fluidic tube, the support feature fixed to the fluidic tube, and the compression screw. ### Claim 3 (depends on 2) The fluidic coupling of claim 2, further comprising a metallic support sleeve surrounding the cylindrical portion configured to support the seal body. ### Claim 4 (depends on 2) A method of fluidic coupling in a chromatography system comprising: providing the fluidic coupling of claim 2; providing the receiver fitting; removably attaching the removable seal device to the compression screw; tightening the compression screw to the receiver fitting; creating a first seal between the first sealing surface and a fitting sealing surface of the receiver fitting; and creating a second seal between the second sealing surface and the end surface of a fluidic tube. ### Claim 5 (depends on 4) The method of claim 4, further comprising: receiving fluid from the fluidic tube by a fluidic channel; and providing the received fluid from the fluidic channel to a channel of the receiver fitting. ### Claim 6 (depends on 5) The method of claim 5, further comprising: loosening the compression screw from the receiver fitting; simultaneously removing the compression screw, the fluidic tube and the removable seal device from the receiver fitting; and unattaching the removable seal device from the compression screw after the simultaneously removing. ### Claim 7 (depends on 6) The method of claim 6, further comprising: providing a second removable seal device having a seal body extending between a first end and a second end, the second removable seal device including an inner channel, wherein the first end of the second removable seal device includes a first sealing surface, and wherein the second removable seal device includes a second sealing surface; removably attaching the second removable seal device to the compression screw; tightening the compression screw to the receiver fitting after the removably attaching the second removable seal device to the compression screw; creating a first seal between the first sealing surface of the second removable seal device and the fitting sealing surface of the receiver fitting; and creating a second seal between the second sealing surface of the second removable seal device and the end surface of a fluidic tube. ### Claim 8 (depends on 4) The method of claim 4, wherein the compression screw is made of metal and wherein the removable seal device is made of a flexible polymer material. ### Claim 9 (depends on 8) The method of claim 8, wherein the support feature is made of metal. ### Claim 10 (depends on 4) The method of claim 4, wherein the support feature extends between a first end and a second end and includes a conical portion proximate the first end that enlarges in diameter as the conical portion extends away from the first end. ### Claim 11 (depends on 2) The fluidic coupling of claim 2, wherein the compression screw is made of metal and wherein the removable seal device is made of a flexible polymer material. ### Claim 12 (depends on 11) The fluidic coupling of claim 11, wherein the support feature is made of metal. ### Claim 13 (depends on 2) The fluidic coupling of claim 2, further comprising the receiver fitting, wherein the receiver fitting includes internal threads configured to engage with the compression screw threaded portion. ### Claim 14 (depends on 2) The fluidic coupling of claim 2, wherein the support feature extends between a first end and a second end and includes a conical portion proximate the first end that enlarges in diameter as the conical portion extends away from the first end. ### Claim 15 A fluidic coupling for use in a chromatography system comprising: a fluidic tube including an end surface; a compression screw having a main body extending along an axis from a first end to a second end, the compression screw including a first threaded portion configured to engage with internal threads of a receiver fitting, the compression screw including an opening extending from the first end to the second end along the axis, wherein the fluidic tube is configured to extend through the opening, the compression screw further including an extending portion extending from the main body to the first end, the extending portion including a smaller diameter than the main body, the extending portion including a second threaded portion; and a removable seal device for fluidic coupling including a seal body extending between a first end and a second end, the seal body including an inner channel configured to receive a flow of a fluid, wherein the first end of the seal body includes a first sealing surface configured to create a first seal with a fitting sealing surface of a receiver fitting, and wherein the seal body incudes a second sealing surface configured to create a second seal with an end of a fluidic tube, wherein the removable seal device is configured to be removably secured to at least one of the fluidic tube, the support feature fixed to the fluidic tube, and a compression screw, such that untightening of the compression screw from the receiver fitting causes the removable seal device to be removed from the receiver fitting, wherein the seal body includes a cylindrical portion extending from the first end, and a conical portion extending from the cylindrical portion and expanding in diameter as the conical portion extends from the cylindrical portion, wherein the cylindrical portion includes an internal bore dimensioned to receive the end of the fluidic tube and a length of the fluidic tube, the seal body further including an internal surface within at least one of the conical portion and a cylindrical extended portion of the conical portion, the internal surface including threads configured to facilitate the removably securing to the at least one of the fluidic tube, the support feature fixed to the fluidic tube, and the compression screw, and wherein the threads of the internal surface of the seal body are configured to engage the second threaded portion of the compression screw. ### Claim 16 (depends on 15) The fluidic coupling of claim 15, further comprising a metallic support sleeve surrounding the cylindrical portion configured to support the seal body. ### Claim 17 (depends on 15) The fluidic coupling of claim 15, wherein the compression screw is made of metal and wherein the removable seal device is made of a flexible polymer material. ### Claim 18 (depends on 17) The fluidic coupling of claim 17, wherein the support feature is made of metal. ### Claim 19 (depends on 15) The fluidic coupling of claim 15, further comprising the receiver fitting, wherein the receiver fitting includes internal threads configured to engage with the first threaded portion of the compression screw. ### Claim 20 (depends on 15) The fluidic coupling of claim 15, wherein the support feature extends between a first end and a second end and includes a conical portion proximate the first end that enlarges in diameter as the conical portion extends away from the first end.