Dibromobenzyl derivative, stereoisomer or salt thereof, and preparation method and application of dibromobenzyl derivative
AssigneeChengdu Shibeikang Biomedical Technology Co., Ltd.
InventorsGuodong Cen, Maoting Yang, Shaojun Tan
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Abstract
A dibromobenzyl derivative with a structure shown as formula I, a stereoisomer or a pharmaceutically acceptable salt thereof and a preparation method and an application of the dibromobenzyl derivative are provided. The dibromobenzyl derivative or the stereoisomer thereof is superior in in-vivo pharmacokinetic stability and drug efficacy, and capable of being used for preparing respiratory drugs, in particular the apophlegmatic drugs.
Claims9
A dibromobenzyl derivative of Formula I, a stereoisomer, or a pharmaceutically acceptable salt thereof,
- wherein, A is five-membered cycloalkane, or adamantane;
- and B is C1-C5 alkane, hydroxyl group, halogen, or halogenated alkane.
A dibromobenzyl derivative, a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein the dibromobenzyl derivative is selected from the group consisting of:
Dependencies are inferred from the claim text.