# US 12,006,272 B1 · Nitrogen activator stabilizer for reducing and protecting nitrogen fertilizer

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- Number: US 12,006,272 B1
- Document ID: US12006272B1
- Status: Granted
- Kind: B1
- Application number: 18/425,949
- Filed: 2024-01-29
- Granted: 2024-06-11
- Earliest claimed: 2023-05-08
- Assignees: King Faisal University
- Applicants: King Faisal University
- Inventors: Hossam El-Din Saad El-Beltagi; Khaled Mohamed Amen Ramadan; Hani Saber Sayed Saudy; Sameh Ahmed Rizk
- Web page: https://patentgrep.com/patent/US12006272B1

## CPC

- C05G 3/44: {for affecting solubility}
- A01C 21/00: Methods of fertilising {, sowing or planting}
- C05B 7/00: Fertilisers based essentially on alkali or ammonium orthophosphates (C05B11/00 takes precedence)
- C05C 1/00: Ammonium nitrate fertilisers
- C05C 9/00: Fertilisers containing urea or urea compounds
- C05C 9/005: {Post-treatment}
- C05C 11/00: Other nitrogenous fertilisers
- C05D 9/02: containing trace elements
- C05F 11/10: Fertilisers containing plant vitamins or hormones
- C05G 1/00: Mixtures of fertilisers belonging individually to different subclasses of C05
- C05G 3/40: for affecting fertiliser dosage or release rate; for affecting solubility
- C05G 5/18: Semi-solid fertilisers, e.g. foams or gels
- C05G 5/30: Layered or coated, e.g. dust-preventing coatings
- C05G 5/38: {layered or coated with wax or resins}
- C07D 473/30: attached in position 6, e.g. hypoxanthine
- C05G: MIXTURES OF FERTILISERS COVERED INDIVIDUALLY BY DIFFERENT SUBCLASSES OF CLASS C05; MIXTURES OF ONE OR MORE FERTILISERS WITH MATERIALS NOT HAVING A SPECIFIC FERTILISING ACTIVITY, e.g. PESTICIDES, SOIL-CONDITIONERS, WETTING AGENTS (organic fertilisers containing added bacterial cultures, mycelia, or the like C05F11/08; organic fertilisers containing plant vitamins or hormones C05F11/10); FERTILISERS CHARACTERISED BY THEIR FORM
- A01C: PLANTING; SOWING; FERTILISING (parts, details or accessories of agricultural machines or implements, in general A01B51/00 - A01B75/00)
- C05B: PHOSPHATIC FERTILISERS
- C05C: NITROGENOUS FERTILISERS
- C05D: INORGANIC FERTILISERS NOT COVERED BY SUBCLASSES C05B, C05C; FERTILISERS PRODUCING CARBON DIOXIDE
- C05F: ORGANIC FERTILISERS NOT COVERED BY SUBCLASSES C05B, C05C, e.g. FERTILISERS FROM WASTE OR REFUSE
- C07D: HETEROCYCLIC COMPOUNDS (macromolecular compounds C08)

## Abstract

A nitrogen activator additive to stabilize nitrogen fertilizer, where the activator is coated onto the nitrogen fertilizer, is provided. The nitrogen activator additive contains the novel compound ABT-PNB, a potassium compound, and chitosan, and provides controlled release of the nitrogen fertilizer which fertilizes crops using reduced levels of the nitrogen fertilizer and reduces the release of greenhouse gasses. Urea is an exemplary nitrogen fertilizer that can be used in this regard.

## Claims

### Claim 1

A method of fertilizing crops, comprising applying a nitrogen activator stabilizer fertilizer (NASF1) composition to said crops; the composition comprising a coated slow-release fertilizer composition comprising:
a core comprising a nitrogen-based fertilizer; and
at least one coating layer surrounding the core, wherein the at least one coating layer comprises a potassium compound, chitosan, and 2-(1-(4-(dimethylamino)butyl)-8-((2-ethoxy-2-oxoethyl)thio)-6-oxo-6,9-dihydro-1H-purin-2-yl)-6-nitrobenzoic acid (ABT-PNB), with the ABT-PNB having the following structure:

### Claim 2 (depends on 1)

The method of claim 1, wherein 1 kg of the coated slow-release fertilizer composition comprising urea as the nitrogen-based fertilizer has an equivalent fertilizing effect as 10 kg of an uncoated fertilizer composition comprising urea.

### Claim 3 (depends on 1)

The method of claim 1, wherein the crops are selected from the group consisting of wheat, corn, olives, palm trees, and any combination thereof.

### Claim 4 (depends on 1)

The method of claim 1, wherein the nitrogen-based fertilizer is urea.

### Claim 5 (depends on 1)

The method of claim 1, wherein the at least one coating layer comprises multiple coating layers.

### Claim 6 (depends on 5)

The method of claim 5, wherein the multiple coating layers comprise two, three, or four coating layers.

### Claim 7 (depends on 5)

The method of claim 5, wherein each of the potassium compound, chitosan, and 2-(1-(4-(dimethylamino)butyl)-8-((2-ethoxy-2-oxoethyl)thio)-6-oxo-6,9-dihydro-1H-purin-2-yl)-6-nitrobenzoic acid are in a separate coating layer of the multiple coating layers.

### Claim 8 (depends on 1)

The method of claim 1, wherein each of the potassium compound, chitosan, and 2-(1-(4-(dimethylamino)butyl)-8-((2-ethoxy-2-oxoethyl)thio)-6-oxo-6,9-dihydro-1H-purin-2-yl)-6-nitrobenzoic acid are in a single coating layer of the at least one coating layer.

### Claim 9 (depends on 1)

The method of claim 1, wherein the potassium compound is selected from the group consisting of potassium phosphate, potassium nitrate, potassium tartrate, and combinations thereof.

### Claim 10 (depends on 4)

The method of claim 4, wherein the at least one coating layer comprises about 1% to about 20% by weight of the potassium compound, about 2% to about 8% by weight of chitosan, and about 1% to about 10% by weight of 2-(1-(4-(dimethylamino)butyl)-8-((2-ethoxy-2-oxoethyl)thio)-6-oxo-6,9-dihydro-1H-purin-2-yl)-6-nitrobenzoic acid.

### Claim 11 (depends on 10)

The method of claim 10, wherein the at least one coating layer comprises about 10% by weight of potassium phosphate, about 5% by weight of chitosan, and about 2% by weight of 2-(1-(4-(dimethylamino)butyl)-8-((2-ethoxy-2-oxoethyl)thio)-6-oxo-6,9-dihydro-1H-purin-2-yl)-6-nitrobenzoic acid.

### Claim 12 (depends on 10)

The method of claim 10, wherein the at least one coating layer comprises about 10% by weight of potassium phosphate, about 5% by weight of chitosan, and about 3% by weight of 2-(1-(4-(dimethylamino)butyl)-8-((2-ethoxy-2-oxoethyl)thio)-6-oxo-6,9-dihydro-1H-purin-2-yl)-6-nitrobenzoic acid.

### Claim 13 (depends on 10)

The method of claim 10, wherein the at least one coating layer comprises about 15% by weight of potassium nitrate, about 5% by weight of chitosan, and about 1% by weight of 2-(1-(4-(dimethylamino)butyl)-8-((2-ethoxy-2-oxoethyl)thio)-6-oxo-6,9-dihydro-1H-purin-2-yl)-6-nitrobenzoic acid.

### Claim 14 (depends on 10)

The method of claim 10, wherein the at least one coating layer comprises about 3% by weight of potassium tartrate, about 5% by weight of chitosan, and about 4% by weight of 2-(1-(4-(dimethylamino)butyl)-8-((2-ethoxy-2-oxoethyl)thio)-6-oxo-6,9-dihydro-1H-purin-2-yl)-6-nitrobenzoic acid.

### Claim 15 (depends on 10)

The method of claim 10, wherein the at least one coating layer comprises about 1% by weight of potassium tartrate, about 5% by weight of chitosan, and about 5% by weight of 2-(1-(4-(dimethylamino)butyl)-8-((2-ethoxy-2-oxoethyl)thio)-6-oxo-6,9-dihydro-1H-purin-2-yl)-6-nitrobenzoic acid.

### Claim 16 (depends on 1)

The method of claim 1, wherein the at least on coating layer permits water to penetrate the composition to contact the fertilizer to produce a fertilizer solution and permits the fertilizer solution to exit the composition and treat crops to which the composition is applied.

### Claim 17 (depends on 1)

The method of claim 1, wherein the composition is a hydrogel.

### Claim 18 (depends on 1)

The method of claim 1, wherein the core comprising the nitrogen-based fertilizer is a nitrogen fixed carbon dot.